OPKO Health, Inc. (OPK) Fair Value 2026

OPK · Diagnostics & Research ·

By CirclFi Research Team · Data from SEC EDGAR, FRED & GDELT

Quality Score

5.6 /10

32 fundamental signals · 1 models active

Value Trap Risk

LOW (33/100)

Quick Summary — As of 2026-08-28, OPKO Health, Inc. (OPK) trades at $1.48. QOC: 5.6/10. Value Trap Risk: 33/100 (LOW). 1/13 models active.

Key Facts

Ticker
OPK
Price
$1.48
Quality Score
5.6/10
Value Trap Risk
33/100
Models Active
1/13
Last Updated
Strength: 1 independent models provide multi-angle coverage
Risk: Majority of models suggest overvaluation

What Fair Value Does Each Model Give OPK?

1 Intrinsic Value Models vs. Current Price ($1.48)

Core Models (Unlocked)
Model Fair Value Upside
Intrinsic · High Conviction
 $0.32 -78.3%

All Models Active

All 1 models are displayed above.

What Is OPKO Health, Inc. (OPK) Worth in 2026?

According to the CirclFi Deep Alpha Valuation Engine, OPKO Health, Inc.'s intrinsic value is estimated at $0.32. Trading at its current price of $1.48, the valuation engine raises significant caution: 1 of 1 models flag downside risk, projecting a median implied return of -78.3%.

What Do the Models Say About OPK?

1 of 13 models are currently active for OPK. All 1 active models suggest the stock trades above fair value. See which stocks rank higher →

How Does OPK Rank in Diagnostics & Research?

Among 52 Diagnostics & Research stocks, OPK ranks #39 by Quality of Company score. CirclFi's QOC score of 5.6/10 evaluates 32 fundamental signals. A score of 5.6 reflects mixed fundamentals.

OPKO Health, Inc.'s positioning within the Diagnostics & Research segment means that FDA approval probability plays an outsized role in fundamental analysis. The sector's unique characteristics — including regulatory pathway clarity — shape both the opportunity set and risk profile.

Is OPK a Value Trap?

CirclFi's Value Trap algorithm assigns OPK a score of 33/100 (LOW). This indicates low risk. The financial profile does not exhibit typical value trap warning signs. The score cross-references apparent undervaluation against fundamental deterioration signals. Browse lowest value-trap stocks →

Multi-Model Methodology

1 of 13 models are active for OPKO Health, Inc.. Limited activation may indicate insufficient history. Each model applies a fundamentally different valuation philosophy. See the complete methodology →

According to the CirclFi Deep Alpha Valuation Engine, OPKO Health, Inc. scores 5.6 out of 10 on our 32-signal quality assessment, a solid rating that maintains reasonable quality metrics with some areas for improvement. The QOC score synthesizes profitability margins, revenue growth reliability, debt management, and capital allocation into a single metric designed to separate durable businesses from statistically cheap ones.

CirclFi runs 13 independent models for each stock. Browse all stocks with 13-model coverage →

Data Sources & Confidence

Every OPK valuation is built from SEC EDGAR XBRL filings — 700+ standardized financial tags. Macroeconomic context from FRED calibrates discount rates, while GDELT news sentiment feeds into our Sentiment SOTP model. All pipelines run daily. Read the complete data methodology →

Across OPK's 1 active models, average confidence is 58%. Moderate confidence indicates reasonable fit.

CirclFi's output is a research starting point, not a buy/sell signal. All data updates daily. Read the full methodology →

This analysis is produced by the CirclFi Valuation Engine using quantitative models applied to SEC EDGAR filings, public market feeds, and FRED macroeconomic indicators. It is not financial advice.

Read the full investment analysis: Should You Buy OPKO Health, Inc. Stock in 2026? →

Bull case, bear case, risk factors & peer comparison — updated daily

Which Similar Diagnostics & Research Stocks Should You Also Analyze?

11 related Diagnostics & Research stocks with 13-model coverage

QUCYQuantum Cyber N.V.QOC 5.6XWELXWELL, Inc.QOC 5.5IMDXInsight Molecular Diagnostics Inc.QOC 6.1ADVBAdvanced Biomed Inc.QOC 5.0GRALGRAIL, Inc.QOC 6.2BIAFbioAffinity Technologies, Inc.QOC 5.0MDXHMDxHealth SAQOC 2.3BLLNBillionToOne, Inc.QOC 7.7PRPOPrecipio, Inc.QOC 6.7IDXXIDEXX Laboratories, Inc.QOC 9.5MEDPMedpace Holdings, Inc.QOC 9.3

Read investment analysis: QUCY · XWEL · IMDX · ADVB · GRAL · BIAF · MDXH · BLLN · PRPO · IDXX · MEDP

Which Other Stocks Have a Similar Quality Score to OPK?

7 companies across all industries closest to OPK’s Quality of Company score of 5.6/10.

BOXLBoxlight CorporationQOC 5.6PLSMPulsenmore Ltd.QOC 5.6ISPRIspire Technology Inc.QOC 5.6LIONLionsgate Studios Corp.QOC 5.6BLSHBullishQOC 5.6ACHCAcadia Healthcare Company, Inc.QOC 5.6NVDANVIDIA CorporationQOC 10.0

Read investment analysis: BOXL · PLSM · ISPR · LION · BLSH · ACHC · NVDA

What Else Do Investors Ask About OPKO Health, Inc.’s Valuation?

What is OPKO Health, Inc.'s intrinsic value in 2026?

CirclFi does not yet have enough active models to publish a median fair value for OPKO Health, Inc. (OPK). The Quality of Company score is 5.6/10 across 32 fundamental signals. All models use SEC EDGAR filings updated daily. See our methodology page for how each model works.

Is OPK overvalued or undervalued right now?

At $1.48, 0 of 1 active models suggest OPK may be undervalued, while 1 indicate potential overvaluation. The assessment depends on which methodology best fits OPKO Health, Inc.'s business model in Diagnostics & Research.

What does a Quality of Company score of 5.6 mean for OPK?

OPKO Health, Inc.'s QOC of 5.6/10 reflects 32 fundamental signals: profitability margins, revenue growth consistency, balance sheet leverage, free cash flow generation, and capital allocation efficiency. Scores between 5-7 reflect moderate fundamentals with areas for improvement.

How many valuation models does CirclFi run on OPK?

CirclFi analyzes OPK with 13 institutional-grade models daily: Bayesian DCF (Monte Carlo + jump-diffusion), EPV (Greenwald zero-growth), EROIC Spread (McKinsey reinvestment), First Chicago (3-scenario), Markov DDM (regime-switching), ML-RIV (machine learning residual income), Dynamic NAV (asset-based), PWERM (option-theoretic), Regime Cross-Sectional (relative), Sentiment SOTP (hybrid), CUCE Ensemble (meta-model), FTNN Topology (neural network), and RCMH-DCF (conditional regime). Currently 1 of 13 are active for this stock. Read the full methodology →

Is OPK a value trap in 2026?

OPKO Health, Inc.'s Value Trap score is 33/100 (LOW). This low score indicates the current valuation is not artificially depressed by fundamental deterioration, suggesting genuine opportunity rather than a trap. Browse stocks by value-trap risk →

Cite this analysis — “CirclFi assigns OPKO Health, Inc. (OPK) a Quality of Company score of 5.6/10 across 32 fundamental signals as of 2026-08-28.” Source: circlfi.com/stock/OPK/ · Methodology
Primary sources for this OPK valuation
  • Financial statements: OPKO Health, Inc. 10-K and 10-Q filings on SEC EDGAR (CIK 0000944809) — 700+ standardized XBRL tags, published by the U.S. Securities and Exchange Commission.
  • Discount-rate inputs: FRED, Federal Reserve Bank of St. Louis — risk-free rates, VIX, yield curve, inflation.
  • News sentiment: The GDELT Project — global media tone, input to the Sentiment SOTP model.
  • Model definitions: CirclFi methodology — the published specification for all 13 models, including the academic sources each one implements.

Market data for OPK as of ; valuations recomputed .