Is OPK or ORGO more undervalued in 2026?

CirclFi compares Opko Health, Inc. (OPK) and Organogenesis Holdings Inc. (ORGO) using 13 institutional-grade valuation models. OPK has a Quality of Company score of 5.9/10 while ORGO scores 7.2/10.

Which is a better buy — OPK or ORGO?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do OPK and ORGO valuations compare?

OPK at $1.46 and ORGO at $2.57 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

OPK vs ORGO Valuation Comparison 2026 — Intrinsic Value Analysis

OPK

Pharmaceutical Preparations

Opko Health, Inc.

Quality

5.9

out of 10

Value Trap

LOW

Price

$1.46

Last close

Models

12/13

Active

ORGO

Pharmaceutical Preparations

Organogenesis Holdings Inc.

Quality

7.2

out of 10

Value Trap

SAFE

Price

$2.57

Last close

Models

12/13

Active

Model-by-Model Comparison

Model	Type	OPK Fair Value	OPK Upside	ORGO Fair Value	ORGO Upside
Bayesian DCF	Intrinsic	$0.22	-84.8%	$0.03	-98.7%
Earnings Power Value	Intrinsic	$0.04	-96.8%	$0.12	-95.2%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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OPK vs ORGO — Which Stock Is More Undervalued?

ORGO scores higher with a 7.2/10 quality rating vs OPK's 5.9/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Opko Health, Inc. (OPK) and Organogenesis Holdings Inc. (ORGO) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

OPK currently trades at $1.46 with a QOC of 5.9/10, while ORGO trades at $2.57 with a QOC of 7.2/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).