AYTU vs BTAI

Aytu BioPharma, Inc. vs BioXcel Therapeutics, Inc. — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — AYTU scores higher on quality with 6.0/10 vs BTAI's 4.4/10. AYTU trades at $2.10 while BTAI trades at $1.19. Both analyzed daily using SEC EDGAR data across 13 institutional models.

AYTU

Drug Manufacturers - Specialty & Generic
Aytu BioPharma, Inc.
Quality
6.0
out of 10
Value Trap
24
SAFE
Price
$2.10
Last close
Models
12/13
Active
VS

BTAI

Drug Manufacturers - Specialty & Generic
BioXcel Therapeutics, Inc.
Quality
4.4
out of 10
Value Trap
24
SAFE
Price
$1.19
Last close
Models
4/13
Active
AYTU
Earnings Power Value sees +199.2% upside
Limited to 2/13 visible models
BTAI
PWERM sees +208.4% upside
Quality 4.4/10 — below average

AYTU vs BTAI — Fair Value Comparison

AYTU
$0$2$5$7 Price$2.10 Bayesian …$2.19 (+4.5%) Earnings …$6.28 (+199.2%)
BTAI
$0$1$3$4 Price$1.19 PWERM$3.67 (+208.4%) EROIC Spr…$1.49 (+24.3%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType AYTU Fair ValueAYTU Upside BTAI Fair ValueBTAI Upside
Bayesian DCF Intrinsic $2.19 +4.5%
Earnings Power Value Intrinsic $6.28 +199.2%
EROIC Spread Intrinsic $5.76 +174.2% $1.49 +24.3%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $2.65 +26.1% $3.67 +208.4%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

AYTU vs BTAI — Which Stock Is More Undervalued in 2026?

AYTU scores higher with a 6.0/10 quality rating vs BTAI's 4.4/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do AYTU and BTAI Valuations Compare?

AYTU currently trades at $2.10 while BTAI trades at $1.19. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily for both companies.

Quality of Company: AYTU vs BTAI

AYTU earns a Quality of Company score of 6.0/10 compared to BTAI's 4.4/10. This moderate difference suggests one company has an edge in fundamental quality, though both may offer investment merit depending on valuation. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: AYTU vs BTAI

AYTU carries a SAFE value trap risk (24/100) while BTAI shows SAFE risk (24/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Drug Manufacturers - Specialty & Generic

Both AYTU and BTAI operate in Drug Manufacturers - Specialty & Generic, which has 79 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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