Is AGIO or AKTX more undervalued in 2026?

CirclFi compares Agios Pharmaceuticals, Inc. (AGIO) and Akari Therapeutics Plc (AKTX) using 13 institutional-grade valuation models. AGIO has a Quality of Company score of 6.0/10 while AKTX scores 1.7/10.

Which is a better buy — AGIO or AKTX?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do AGIO and AKTX valuations compare?

AGIO at $30.42 and AKTX at $22.05 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

AGIO vs AKTX Valuation Comparison 2026 — Intrinsic Value Analysis

AGIO

Biotechnology

Agios Pharmaceuticals, Inc.

Quality

6.0

out of 10

Value Trap

SAFE

Price

$30.42

Last close

Models

12/13

Active

AKTX

Biotechnology

Akari Therapeutics Plc

Quality

1.7

out of 10

Value Trap

SAFE

Price

$22.05

Last close

Models

7/13

Active

Model-by-Model Comparison

Model	Type	AGIO Fair Value	AGIO Upside	AKTX Fair Value	AKTX Upside
Bayesian DCF	Intrinsic	$8.83	-71.0%	$5.78	-73.8%
Earnings Power Value	Intrinsic	$3.81	-86.5%	—	—
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$28.76	-5.4%	$23.73	+307.8%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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AGIO vs AKTX — Which Stock Is More Undervalued?

AGIO scores higher with a 6.0/10 quality rating vs AKTX's 1.7/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Agios Pharmaceuticals, Inc. (AGIO) and Akari Therapeutics Plc (AKTX) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

AGIO currently trades at $30.42 with a QOC of 6.0/10, while AKTX trades at $22.05 with a QOC of 1.7/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).