Is XERS or XNCR more undervalued in 2026?

CirclFi compares Xeris Biopharma Holdings, Inc. (XERS) and Xencor, Inc. (XNCR) using 13 institutional-grade valuation models. XERS has a Quality of Company score of 8.6/10 while XNCR scores 6.1/10.

Which is a better buy — XERS or XNCR?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do XERS and XNCR valuations compare?

XERS at $6.16 and XNCR at $11.88 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

XERS vs XNCR Valuation Comparison 2026 — Intrinsic Value Analysis

XERS

Pharmaceutical Preparations

Xeris Biopharma Holdings, Inc.

Quality

8.6

out of 10

Value Trap

LOW

Price

$6.16

Last close

Models

11/13

Active

XNCR

Pharmaceutical Preparations

Xencor, Inc.

Quality

6.1

out of 10

Value Trap

SAFE

Price

$11.88

Last close

Models

9/13

Active

Model-by-Model Comparison

Model	Type	XERS Fair Value	XERS Upside	XNCR Fair Value	XNCR Upside
Bayesian DCF	Intrinsic	$1.45	-76.5%	$1.58	-86.7%
Earnings Power Value	Intrinsic	$0.13	-97.8%	—	—
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$1.73	-72.2%	$0.99	-91.2%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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XERS vs XNCR — Which Stock Is More Undervalued?

XERS scores higher with a 8.6/10 quality rating vs XNCR's 6.1/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Xeris Biopharma Holdings, Inc. (XERS) and Xencor, Inc. (XNCR) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

XERS currently trades at $6.16 with a QOC of 8.6/10, while XNCR trades at $11.88 with a QOC of 6.1/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).