Is TXMD or TYRA more undervalued in 2026?

CirclFi compares TherapeuticsMD, Inc. (TXMD) and Tyra Biosciences, Inc. (TYRA) using 13 institutional-grade valuation models. TXMD has a Quality of Company score of 6.5/10 while TYRA scores 4.3/10.

Which is a better buy — TXMD or TYRA?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do TXMD and TYRA valuations compare?

TXMD at $2.14 and TYRA at $33.41 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

TXMD vs TYRA Valuation Comparison 2026 — Intrinsic Value Analysis

TXMD

Pharmaceutical Preparations

TherapeuticsMD, Inc.

Quality

6.5

out of 10

Value Trap

LOW

Price

$2.14

Last close

Models

12/13

Active

TYRA

Pharmaceutical Preparations

Tyra Biosciences, Inc.

Quality

4.3

out of 10

Value Trap

SAFE

Price

$33.41

Last close

Models

7/13

Active

Model-by-Model Comparison

Model	Type	TXMD Fair Value	TXMD Upside	TYRA Fair Value	TYRA Upside
Bayesian DCF	Intrinsic	$4.61	+115.3%	$9.65	-71.1%
Earnings Power Value	Intrinsic	$0.75	-63.7%	—	—
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$6.63	+210.0%	$5.32	-84.1%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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TXMD vs TYRA — Which Stock Is More Undervalued?

TXMD scores higher with a 6.5/10 quality rating vs TYRA's 4.3/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing TherapeuticsMD, Inc. (TXMD) and Tyra Biosciences, Inc. (TYRA) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

TXMD currently trades at $2.14 with a QOC of 6.5/10, while TYRA trades at $33.41 with a QOC of 4.3/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).