Is TVRD or TYRA more undervalued in 2026?

CirclFi compares Tvardi Therapeutics, Inc. (TVRD) and Tyra Biosciences, Inc. (TYRA) using 13 institutional-grade valuation models. TVRD has a Quality of Company score of 4.1/10 while TYRA scores 4.3/10.

Which is a better buy — TVRD or TYRA?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do TVRD and TYRA valuations compare?

TVRD at $3.49 and TYRA at $32.68 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

TVRD vs TYRA Valuation Comparison 2026 — Intrinsic Value Analysis

TVRD

Biotechnology

Tvardi Therapeutics, Inc.

Quality

4.1

out of 10

Value Trap

LOW

Price

$3.49

Last close

Models

7/13

Active

TYRA

Biotechnology

Tyra Biosciences, Inc.

Quality

4.3

out of 10

Value Trap

SAFE

Price

$32.68

Last close

Models

7/13

Active

Model-by-Model Comparison

Model	Type	TVRD Fair Value	TVRD Upside	TYRA Fair Value	TYRA Upside
Bayesian DCF	Intrinsic	$2.17	-28.9%	$9.52	-70.9%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$3.04	-3.1%	$5.32	-83.7%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%

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TVRD vs TYRA — Which Stock Is More Undervalued?

TYRA scores higher with a 4.3/10 quality rating vs TVRD's 4.1/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Tvardi Therapeutics, Inc. (TVRD) and Tyra Biosciences, Inc. (TYRA) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

TVRD currently trades at $3.49 with a QOC of 4.1/10, while TYRA trades at $32.68 with a QOC of 4.3/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).