SNTI vs SRPT

Senti Biosciences Holdings, Inc vs Sarepta Therapeutics, Inc. — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — SRPT scores higher on quality with 7.5/10 vs SNTI's 4.1/10. SNTI trades at $0.98 while SRPT trades at $16.25. Both analyzed daily using SEC EDGAR data across 13 institutional models.

SNTI

Biotechnology
Senti Biosciences Holdings, Inc
Quality
4.1
out of 10
Value Trap
39
LOW
Price
$0.98
Last close
Models
9/13
Active
VS

SRPT

Biotechnology
Sarepta Therapeutics, Inc.
Quality
7.5
out of 10
Value Trap
12
SAFE
Price
$16.25
Last close
Models
12/13
Active
SNTI
2 models active
Quality 4.1/10 — below average
SRPT
2 models active
Limited to 2/13 visible models

SNTI vs SRPT — Fair Value Comparison

SNTI
$0$0$1$1 Price$0.98 Bayesian …$0.52 (-48.4%) Dynamic N…$0.06 (-93.6%)
SRPT
$0$6$13$19 Price$16.25 Bayesian …$0.86 (-94.7%) Earnings …$4.59 (-77.4%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType SNTI Fair ValueSNTI Upside SRPT Fair ValueSRPT Upside
Bayesian DCF Intrinsic $0.52 -48.4% $0.86 -94.7%
Earnings Power Value Intrinsic $4.59 -77.4%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $0.06 -93.6% $14.45 -11.1%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

SNTI vs SRPT — Which Stock Is More Undervalued in 2026?

SRPT scores higher with a 7.5/10 quality rating vs SNTI's 4.1/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do SNTI and SRPT Valuations Compare?

At $0.98, SNTI trades +48.4% above its Bayesian DCF fair value of $0.52, while SRPT at $16.25 trades +94.7% above its estimate of $0.86. SRPT shows a wider gap between price and intrinsic value.

Quality of Company: SNTI vs SRPT

SNTI earns a Quality of Company score of 4.1/10 compared to SRPT's 7.5/10. This is a significant quality gap — the higher-scoring company demonstrates materially stronger fundamentals across profitability, growth consistency, and balance sheet health. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: SNTI vs SRPT

SNTI carries a LOW value trap risk (39/100) while SRPT shows SAFE risk (12/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both SNTI and SRPT operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

2 of 13 MODELS UNLOCKED

You’re comparing 2 models. 11 more have an opinion.

11 hidden models compare SNTI vs SRPT differently — including EROIC Spread, First Chicago, Markov DDM, PWERM, and 7 more. Some may disagree with the 2 you see above.

11 additional fair values per stock Full confidence breakdown Live terminal — 5,000+ stocks

Bloomberg Terminal: ~$2,000/mo  ·  FactSet: ~$1,000/mo  ·  CirclFi: $0.90/day

See All 13 Models — $0.90/day

We don’t predict prices. We show you what 13 independent mathematical frameworks say a stock is worth — and let you decide.

See all Biotechnology stocks →