Is SDGR or SOPH more undervalued in 2026?

CirclFi compares Schrodinger, Inc. (SDGR) and SOPHiA GENETICS SA (SOPH) using 13 institutional-grade valuation models. SDGR has a Quality of Company score of 7.5/10 while SOPH scores 5.7/10.

Which is a better buy — SDGR or SOPH?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do SDGR and SOPH valuations compare?

SDGR at $14.16 and SOPH at $5.08 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

SDGR vs SOPH Valuation Comparison 2026 — Intrinsic Value Analysis

SDGR

Health Information Services

Schrodinger, Inc.

Quality

7.5

out of 10

Value Trap

SAFE

Price

$14.16

Last close

Models

12/13

Active

SOPH

Health Information Services

SOPHiA GENETICS SA

Quality

5.7

out of 10

Value Trap

SAFE

Price

$5.08

Last close

Models

10/13

Active

Model-by-Model Comparison

Model	Type	SDGR Fair Value	SDGR Upside	SOPH Fair Value	SOPH Upside
Bayesian DCF	Intrinsic	$15.76	+11.3%	$1.31	-74.3%
Earnings Power Value	Intrinsic	$6.34	-48.8%	$2.53	-52.5%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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SDGR vs SOPH — Which Stock Is More Undervalued?

SDGR scores higher with a 7.5/10 quality rating vs SOPH's 5.7/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Schrodinger, Inc. (SDGR) and SOPHiA GENETICS SA (SOPH) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

SDGR currently trades at $14.16 with a QOC of 7.5/10, while SOPH trades at $5.08 with a QOC of 5.7/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).