Is SCYX or SEPN more undervalued in 2026?

CirclFi compares SCYNEXIS, Inc. (SCYX) and Septerna, Inc. (SEPN) using 13 institutional-grade valuation models. SCYX has a Quality of Company score of 5.6/10 while SEPN scores 7.0/10.

Which is a better buy — SCYX or SEPN?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do SCYX and SEPN valuations compare?

SCYX at $0.70 and SEPN at $30.20 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

SCYX vs SEPN Valuation Comparison 2026 — Intrinsic Value Analysis

SCYX

Pharmaceutical Preparations

SCYNEXIS, Inc.

Quality

5.6

out of 10

Value Trap

LOW

Price

$0.70

Last close

Models

10/13

Active

SEPN

Pharmaceutical Preparations

Septerna, Inc.

Quality

7.0

out of 10

Value Trap

SAFE

Price

$30.20

Last close

Models

10/13

Active

Model-by-Model Comparison

Model	Type	SCYX Fair Value	SCYX Upside	SEPN Fair Value	SEPN Upside
Bayesian DCF	Intrinsic	$0.38	-46.8%	$15.60	-48.3%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$0.84	+19.7%	$4.39	-85.5%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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SCYX vs SEPN — Which Stock Is More Undervalued?

SEPN scores higher with a 7.0/10 quality rating vs SCYX's 5.6/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing SCYNEXIS, Inc. (SCYX) and Septerna, Inc. (SEPN) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

SCYX currently trades at $0.70 with a QOC of 5.6/10, while SEPN trades at $30.20 with a QOC of 7.0/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).