SCNI vs SEPN

Scinai Immunotherapeutics Ltd. vs Septerna, Inc. — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — SEPN scores higher on quality with 6.9/10 vs SCNI's 1.9/10. SCNI trades at $0.48 while SEPN trades at $29.94. Both analyzed daily using SEC EDGAR data across 13 institutional models.

SCNI

Biotechnology
Scinai Immunotherapeutics Ltd.
Quality
1.9
out of 10
Value Trap
12
SAFE
Price
$0.48
Last close
Models
9/13
Active
VS

SEPN

Biotechnology
Septerna, Inc.
Quality
6.9
out of 10
Value Trap
12
SAFE
Price
$29.94
Last close
Models
10/13
Active
SCNI
2 models active
Quality 1.9/10 — below average
SEPN
2 models active
Limited to 2/13 visible models

SCNI vs SEPN — Fair Value Comparison

SCNI
$0$0$0$1 Price$0.48 Bayesian …$0.12 (-74.0%) Regime Cr…$0.06 (-87.8%)
SEPN
$0$12$24$35 Price$29.94 Bayesian …$15.33 (-48.8%) Dynamic N…$4.39 (-85.3%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType SCNI Fair ValueSCNI Upside SEPN Fair ValueSEPN Upside
Bayesian DCF Intrinsic $0.12 -74.0% $15.33 -48.8%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $0.36 -25.5% $4.39 -85.3%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $0.06 -87.8% $3.46 -88.5%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

SCNI vs SEPN — Which Stock Is More Undervalued in 2026?

SEPN scores higher with a 6.9/10 quality rating vs SCNI's 1.9/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do SCNI and SEPN Valuations Compare?

At $0.48, SCNI trades +74.0% above its Bayesian DCF fair value of $0.12, while SEPN at $29.94 trades +48.8% above its estimate of $15.33. SCNI shows a wider gap between price and intrinsic value.

Quality of Company: SCNI vs SEPN

SCNI earns a Quality of Company score of 1.9/10 compared to SEPN's 6.9/10. This is a significant quality gap — the higher-scoring company demonstrates materially stronger fundamentals across profitability, growth consistency, and balance sheet health. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: SCNI vs SEPN

SCNI carries a SAFE value trap risk (12/100) while SEPN shows SAFE risk (12/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both SCNI and SEPN operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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