KOD vs KPTI

Kodiak Sciences Inc vs Karyopharm Therapeutics Inc. — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — KPTI scores higher on quality with 5.1/10 vs KOD's 4.8/10. KOD trades at $33.22 while KPTI trades at $9.23. Both analyzed daily using SEC EDGAR data across 13 institutional models.

KOD

Biotechnology
Kodiak Sciences Inc
Quality
4.8
out of 10
Value Trap
12
SAFE
Price
$33.22
Last close
Models
10/13
Active
VS

KPTI

Biotechnology
Karyopharm Therapeutics Inc.
Quality
5.1
out of 10
Value Trap
30
LOW
Price
$9.23
Last close
Models
7/13
Active
KOD
2 models active
Quality 4.8/10 — below average
KPTI
PWERM sees +173.0% upside
Limited to 2/13 visible models

KOD vs KPTI — Fair Value Comparison

KOD
$0$13$26$39 Price$33.22 Bayesian …$10.92 (-67.1%) Earnings …$23.98 (-46.5%)
KPTI
$0$10$20$30 Price$9.23 Bayesian …$3.33 (-64.0%) PWERM$25.20 (+173.0%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType KOD Fair ValueKOD Upside KPTI Fair ValueKPTI Upside
Bayesian DCF Intrinsic $10.92 -67.1% $3.33 -64.0%
Earnings Power Value Intrinsic $23.98 -46.5%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $33.84 +1.9% $25.20 +173.0%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%

KOD vs KPTI — Which Stock Is More Undervalued in 2026?

KPTI scores higher with a 5.1/10 quality rating vs KOD's 4.8/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do KOD and KPTI Valuations Compare?

At $33.22, KOD trades +67.1% above its Bayesian DCF fair value of $10.92, while KPTI at $9.23 trades +64.0% above its estimate of $3.33. KOD shows a wider gap between price and intrinsic value.

Quality of Company: KOD vs KPTI

KOD earns a Quality of Company score of 4.8/10 compared to KPTI's 5.1/10. The scores are closely matched, indicating similar fundamental quality profiles. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: KOD vs KPTI

KOD carries a SAFE value trap risk (12/100) while KPTI shows LOW risk (30/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both KOD and KPTI operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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