Is ILMN or NAUT more undervalued in 2026?

CirclFi compares Illumina, Inc. (ILMN) and Nautilus Biotechnology, Inc. (NAUT) using 13 institutional-grade valuation models. ILMN has a Quality of Company score of 8.5/10 while NAUT scores 4.3/10.

Which is a better buy — ILMN or NAUT?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do ILMN and NAUT valuations compare?

ILMN at $162.96 and NAUT at $2.74 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

ILMN vs NAUT Valuation Comparison 2026 — Intrinsic Value Analysis

ILMN

Laboratory Analytical Instruments

Illumina, Inc.

Quality

8.5

out of 10

Value Trap

SAFE

Price

$162.96

Last close

Models

13/13

Active

NAUT

Laboratory Analytical Instruments

Nautilus Biotechnology, Inc.

Quality

4.3

out of 10

Value Trap

SAFE

Price

$2.74

Last close

Models

7/13

Active

Model-by-Model Comparison

Model	Type	ILMN Fair Value	ILMN Upside	NAUT Fair Value	NAUT Upside
Bayesian DCF	Intrinsic	$53.35	-67.3%	$0.61	-77.6%
Earnings Power Value	Intrinsic	$131.24	-19.5%	—	—
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$14.64	-91.0%	$0.86	-68.7%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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ILMN vs NAUT — Which Stock Is More Undervalued?

ILMN scores higher with a 8.5/10 quality rating vs NAUT's 4.3/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Illumina, Inc. (ILMN) and Nautilus Biotechnology, Inc. (NAUT) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

ILMN currently trades at $162.96 with a QOC of 8.5/10, while NAUT trades at $2.74 with a QOC of 4.3/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).