Is APVO or ARGX more undervalued in 2026?

CirclFi compares Aptevo Therapeutics Inc. (APVO) and argenx SE (ARGX) using 13 institutional-grade valuation models. APVO has a Quality of Company score of 4.2/10 while ARGX scores 2.0/10.

Which is a better buy — APVO or ARGX?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do APVO and ARGX valuations compare?

APVO at $5.00 and ARGX at $838.49 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

APVO vs ARGX Valuation Comparison 2026 — Intrinsic Value Analysis

APVO

Biotechnology

Aptevo Therapeutics Inc.

Quality

4.2

out of 10

Value Trap

SAFE

Price

$5.00

Last close

Models

6/13

Active

ARGX

Biotechnology

argenx SE

Quality

2.0

out of 10

Value Trap

—

Price

$838.49

Last close

Models

13/13

Active

Model-by-Model Comparison

Model	Type	APVO Fair Value	APVO Upside	ARGX Fair Value	ARGX Upside
Bayesian DCF	Intrinsic	$6.12	+22.5%	$279.55	-66.7%
Earnings Power Value	Intrinsic	—	—	$363.38	-53.4%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$0.36	-92.6%	$1161.33	+38.5%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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APVO vs ARGX — Which Stock Is More Undervalued?

APVO scores higher with a 4.2/10 quality rating vs ARGX's 2.0/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Aptevo Therapeutics Inc. (APVO) and argenx SE (ARGX) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

APVO currently trades at $5.00 with a QOC of 4.2/10, while ARGX trades at $838.49 with a QOC of 2.0/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).