AMGN vs AZN

Amgen Inc. vs AstraZeneca PLC — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — AZN scores higher on quality with 10.0/10 vs AMGN's 9.0/10. AMGN trades at $328.26 while AZN trades at $177.45. Both analyzed daily using SEC EDGAR data across 13 institutional models.

AMGN

Drug Manufacturers - General
Amgen Inc.
Quality
9.0
out of 10
Value Trap
12
SAFE
Price
$328.26
Last close
Models
12/13
Active
VS

AZN

Drug Manufacturers - General
AstraZeneca PLC
Quality
10.0
out of 10
Value Trap
6
SAFE
Price
$177.45
Last close
Models
12/13
Active
AMGN
Quality Score 9.0/10 — top tier
Limited to 2/13 visible models
AZN
Quality Score 10.0/10 — top tier
Limited to 2/13 visible models

AMGN vs AZN — Fair Value Comparison

AMGN
$0$129$258$387 Price$328.26 Bayesian …$105.47 (-67.9%) Earnings …$217.41 (-33.8%)
AZN
$0$70$140$209 Price$177.45 Bayesian …$118.84 (-33.0%) Earnings …$72.98 (-58.9%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType AMGN Fair ValueAMGN Upside AZN Fair ValueAZN Upside
Bayesian DCF Intrinsic $105.47 -67.9% $118.84 -33.0%
Earnings Power Value Intrinsic $217.41 -33.8% $72.98 -58.9%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

AMGN vs AZN — Which Stock Is More Undervalued in 2026?

AZN scores higher with a 10.0/10 quality rating vs AMGN's 9.0/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do AMGN and AZN Valuations Compare?

At $328.26, AMGN trades +67.9% above its Bayesian DCF fair value of $105.47, while AZN at $177.45 trades +33.0% above its estimate of $118.84. AMGN shows a wider gap between price and intrinsic value.

Quality of Company: AMGN vs AZN

AMGN earns a Quality of Company score of 9.0/10 compared to AZN's 10.0/10. The scores are closely matched, indicating similar fundamental quality profiles. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: AMGN vs AZN

AMGN carries a SAFE value trap risk (12/100) while AZN shows SAFE risk (6/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Drug Manufacturers - General

Both AMGN and AZN operate in Drug Manufacturers - General, which has 20 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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