TWST vs WAT

Twist Bioscience Corporation vs Waters Corporation — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — WAT scores higher on quality with 5.7/10 vs TWST's 4.5/10. TWST trades at $70.15 while WAT trades at $371.93. Both analyzed daily using SEC EDGAR data across 13 institutional models.

TWST

Diagnostics & Research
Twist Bioscience Corporation
Quality
4.5
out of 10
Value Trap
23
SAFE
Price
$70.15
Last close
Models
11/13
Active
VS

WAT

Diagnostics & Research
Waters Corporation
Quality
5.7
out of 10
Value Trap
23
SAFE
Price
$371.93
Last close
Models
12/13
Active
TWST
2 models active
Quality 4.5/10 — below average
WAT
2 models active
Limited to 2/13 visible models

TWST vs WAT — Fair Value Comparison

TWST
$0$28$55$83 Price$70.15 Bayesian …$21.37 (-69.5%) Earnings …$29.92 (-50.9%)
WAT
$0$146$293$439 Price$371.93 Bayesian …$14.21 (-96.2%) Earnings …$36.66 (-89.7%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType TWST Fair ValueTWST Upside WAT Fair ValueWAT Upside
Bayesian DCF Intrinsic $21.37 -69.5% $14.21 -96.2%
Earnings Power Value Intrinsic $29.92 -50.9% $36.66 -89.7%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

TWST vs WAT — Which Stock Is More Undervalued in 2026?

WAT scores higher with a 5.7/10 quality rating vs TWST's 4.5/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do TWST and WAT Valuations Compare?

At $70.15, TWST trades +69.5% above its Bayesian DCF fair value of $21.37, while WAT at $371.93 trades +96.2% above its estimate of $14.21. WAT shows a wider gap between price and intrinsic value.

Quality of Company: TWST vs WAT

TWST earns a Quality of Company score of 4.5/10 compared to WAT's 5.7/10. This moderate difference suggests one company has an edge in fundamental quality, though both may offer investment merit depending on valuation. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: TWST vs WAT

TWST carries a SAFE value trap risk (23/100) while WAT shows SAFE risk (23/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Diagnostics & Research

Both TWST and WAT operate in Diagnostics & Research, which has 48 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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