Is TRVI or TYRA more undervalued in 2026?

CirclFi compares Trevi Therapeutics, Inc. (TRVI) and Tyra Biosciences, Inc. (TYRA) using 13 institutional-grade valuation models. TRVI has a Quality of Company score of 4.2/10 while TYRA scores 4.3/10.

Which is a better buy — TRVI or TYRA?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do TRVI and TYRA valuations compare?

TRVI at $14.14 and TYRA at $33.41 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

TRVI vs TYRA Valuation Comparison 2026 — Intrinsic Value Analysis

TRVI

Pharmaceutical Preparations

Trevi Therapeutics, Inc.

Quality

4.2

out of 10

Value Trap

LOW

Price

$14.14

Last close

Models

7/13

Active

TYRA

Pharmaceutical Preparations

Tyra Biosciences, Inc.

Quality

4.3

out of 10

Value Trap

SAFE

Price

$33.41

Last close

Models

7/13

Active

Model-by-Model Comparison

Model	Type	TRVI Fair Value	TRVI Upside	TYRA Fair Value	TYRA Upside
Bayesian DCF	Intrinsic	$3.83	-72.9%	$9.65	-71.1%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$0.36	-97.4%	$1.50	-95.5%
Dynamic NAV	Asset-Based	$1.06	-92.5%	$5.32	-84.1%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%

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TRVI vs TYRA — Which Stock Is More Undervalued?

TYRA scores higher with a 4.3/10 quality rating vs TRVI's 4.2/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Trevi Therapeutics, Inc. (TRVI) and Tyra Biosciences, Inc. (TYRA) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

TRVI currently trades at $14.14 with a QOC of 4.2/10, while TYRA trades at $33.41 with a QOC of 4.3/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).