Is TPST or TSHA more undervalued in 2026?

CirclFi compares Tempest Therapeutics, Inc. (TPST) and Taysha Gene Therapies, Inc. (TSHA) using 13 institutional-grade valuation models. TPST has a Quality of Company score of 3.2/10 while TSHA scores 6.0/10.

Which is a better buy — TPST or TSHA?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do TPST and TSHA valuations compare?

TPST at $1.73 and TSHA at $5.92 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

TPST vs TSHA Valuation Comparison 2026 — Intrinsic Value Analysis

TPST

Biotechnology

Tempest Therapeutics, Inc.

Quality

3.2

out of 10

Value Trap

LOW

Price

$1.73

Last close

Models

7/13

Active

TSHA

Biotechnology

Taysha Gene Therapies, Inc.

Quality

6.0

out of 10

Value Trap

SAFE

Price

$5.92

Last close

Models

9/13

Active

Model-by-Model Comparison

Model	Type	TPST Fair Value	TPST Upside	TSHA Fair Value	TSHA Upside
Bayesian DCF	Intrinsic	$0.32	-81.3%	$2.02	-65.8%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$5.58	+222.6%	$1.05	-82.3%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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TPST vs TSHA — Which Stock Is More Undervalued?

TSHA scores higher with a 6.0/10 quality rating vs TPST's 3.2/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Tempest Therapeutics, Inc. (TPST) and Taysha Gene Therapies, Inc. (TSHA) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

TPST currently trades at $1.73 with a QOC of 3.2/10, while TSHA trades at $5.92 with a QOC of 6.0/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).