SNSE vs SNTI

Sensei Biotherapeutics, Inc. vs Senti Biosciences Holdings, Inc — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — SNTI scores higher on quality with 4.1/10 vs SNSE's 3.7/10. SNSE trades at $16.09 while SNTI trades at $0.98. Both analyzed daily using SEC EDGAR data across 13 institutional models.

SNSE

Biotechnology
Sensei Biotherapeutics, Inc.
Quality
3.7
out of 10
Value Trap
36
LOW
Price
$16.09
Last close
Models
4/13
Active
VS

SNTI

Biotechnology
Senti Biosciences Holdings, Inc
Quality
4.1
out of 10
Value Trap
39
LOW
Price
$0.98
Last close
Models
9/13
Active
SNSE
Bayesian DCF sees +309.9% upside
Quality 3.7/10 — below average
SNTI
2 models active
Quality 4.1/10 — below average

SNSE vs SNTI — Fair Value Comparison

SNSE
$0$26$52$78 Price$16.09 Bayesian …$65.97 (+309.9%) ML-RIV$1.33 (-95.1%)
SNTI
$0$0$1$1 Price$0.98 Bayesian …$0.52 (-48.4%) Dynamic N…$0.06 (-93.6%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType SNSE Fair ValueSNSE Upside SNTI Fair ValueSNTI Upside
Bayesian DCF Intrinsic $65.97 +309.9% $0.52 -48.4%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $1.33 -95.1% $2.22 +125.7%
Dynamic NAV Asset-Based $0.06 -93.6%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%

SNSE vs SNTI — Which Stock Is More Undervalued in 2026?

SNTI scores higher with a 4.1/10 quality rating vs SNSE's 3.7/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do SNSE and SNTI Valuations Compare?

At $16.09, SNSE trades +309.9% below its Bayesian DCF fair value of $65.97, while SNTI at $0.98 trades +48.4% above its estimate of $0.52. SNSE shows a wider gap between price and intrinsic value.

Quality of Company: SNSE vs SNTI

SNSE earns a Quality of Company score of 3.7/10 compared to SNTI's 4.1/10. The scores are closely matched, indicating similar fundamental quality profiles. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: SNSE vs SNTI

SNSE carries a LOW value trap risk (36/100) while SNTI shows LOW risk (39/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both SNSE and SNTI operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

2 of 13 MODELS UNLOCKED

You’re comparing 2 models. 11 more have an opinion.

11 hidden models compare SNSE vs SNTI differently — including EROIC Spread, First Chicago, Markov DDM, PWERM, and 7 more. Some may disagree with the 2 you see above.

11 additional fair values per stock Full confidence breakdown Live terminal — 5,000+ stocks

Bloomberg Terminal: ~$2,000/mo  ·  FactSet: ~$1,000/mo  ·  CirclFi: $0.90/day

See All 13 Models — $0.90/day

We don’t predict prices. We show you what 13 independent mathematical frameworks say a stock is worth — and let you decide.

See all Biotechnology stocks →