SNDX vs SNTI

Syndax Pharmaceuticals, Inc. vs Senti Biosciences Holdings, Inc — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — SNDX scores higher on quality with 5.7/10 vs SNTI's 4.1/10. SNDX trades at $18.39 while SNTI trades at $0.98. Both analyzed daily using SEC EDGAR data across 13 institutional models.

SNDX

Biotechnology
Syndax Pharmaceuticals, Inc.
Quality
5.7
out of 10
Value Trap
30
LOW
Price
$18.39
Last close
Models
9/13
Active
VS

SNTI

Biotechnology
Senti Biosciences Holdings, Inc
Quality
4.1
out of 10
Value Trap
39
LOW
Price
$0.98
Last close
Models
9/13
Active
SNDX
2 models active
Limited to 2/13 visible models
SNTI
2 models active
Quality 4.1/10 — below average

SNDX vs SNTI — Fair Value Comparison

SNDX
$0$7$14$22 Price$18.39 Bayesian …$0.71 (-96.1%) Earnings …$2.58 (-87.9%)
SNTI
$0$0$1$1 Price$0.98 Bayesian …$0.52 (-48.4%) Dynamic N…$0.06 (-93.6%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType SNDX Fair ValueSNDX Upside SNTI Fair ValueSNTI Upside
Bayesian DCF Intrinsic $0.71 -96.1% $0.52 -48.4%
Earnings Power Value Intrinsic $2.58 -87.9%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $1.67 -90.9% $0.06 -93.6%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%

SNDX vs SNTI — Which Stock Is More Undervalued in 2026?

SNDX scores higher with a 5.7/10 quality rating vs SNTI's 4.1/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do SNDX and SNTI Valuations Compare?

At $18.39, SNDX trades +96.1% above its Bayesian DCF fair value of $0.71, while SNTI at $0.98 trades +48.4% above its estimate of $0.52. SNDX shows a wider gap between price and intrinsic value.

Quality of Company: SNDX vs SNTI

SNDX earns a Quality of Company score of 5.7/10 compared to SNTI's 4.1/10. This moderate difference suggests one company has an edge in fundamental quality, though both may offer investment merit depending on valuation. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: SNDX vs SNTI

SNDX carries a LOW value trap risk (30/100) while SNTI shows LOW risk (39/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both SNDX and SNTI operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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