SHC vs TWST

Sotera Health Company vs Twist Bioscience Corporation — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — SHC scores higher on quality with 8.7/10 vs TWST's 4.5/10. SHC trades at $15.02 while TWST trades at $70.15. Both analyzed daily using SEC EDGAR data across 13 institutional models.

SHC

Diagnostics & Research
Sotera Health Company
Quality
8.7
out of 10
Value Trap
Price
$15.02
Last close
Models
11/13
Active
VS

TWST

Diagnostics & Research
Twist Bioscience Corporation
Quality
4.5
out of 10
Value Trap
23
SAFE
Price
$70.15
Last close
Models
11/13
Active
SHC
Quality Score 8.7/10 — top tier
Limited to 2/13 visible models
TWST
2 models active
Quality 4.5/10 — below average

SHC vs TWST — Fair Value Comparison

SHC
$0$6$12$18 Price$15.02 Bayesian …$8.84 (-43.5%) Markov DDM$2.21 (-85.8%)
TWST
$0$28$55$83 Price$70.15 Bayesian …$21.37 (-69.5%) Earnings …$29.92 (-50.9%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType SHC Fair ValueSHC Upside TWST Fair ValueTWST Upside
Bayesian DCF Intrinsic $8.84 -43.5% $21.37 -69.5%
Earnings Power Value Intrinsic $29.92 -50.9%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $2.21 -85.8% $10.60 -82.6%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

SHC vs TWST — Which Stock Is More Undervalued in 2026?

SHC scores higher with a 8.7/10 quality rating vs TWST's 4.5/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do SHC and TWST Valuations Compare?

At $15.02, SHC trades +43.5% above its Bayesian DCF fair value of $8.84, while TWST at $70.15 trades +69.5% above its estimate of $21.37. TWST shows a wider gap between price and intrinsic value.

Quality of Company: SHC vs TWST

SHC earns a Quality of Company score of 8.7/10 compared to TWST's 4.5/10. This is a significant quality gap — the higher-scoring company demonstrates materially stronger fundamentals across profitability, growth consistency, and balance sheet health. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: SHC vs TWST

Review the value trap analysis for both SHC and TWST to assess whether apparent undervaluation reflects genuine opportunity or hidden fundamental risk.

Both in Diagnostics & Research

Both SHC and TWST operate in Diagnostics & Research, which has 48 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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