Is LSTA or LYEL more undervalued in 2026?

CirclFi compares Lisata Therapeutics, Inc. (LSTA) and Lyell Immunopharma, Inc. (LYEL) using 13 institutional-grade valuation models. LSTA has a Quality of Company score of 5.2/10 while LYEL scores 4.8/10.

Which is a better buy — LSTA or LYEL?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do LSTA and LYEL valuations compare?

LSTA at $3.30 and LYEL at $16.83 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

LSTA vs LYEL Valuation Comparison 2026 — Intrinsic Value Analysis

LSTA

Biotechnology

Lisata Therapeutics, Inc.

Quality

5.2

out of 10

Value Trap

SAFE

Price

$3.30

Last close

Models

9/13

Active

LYEL

Biotechnology

Lyell Immunopharma, Inc.

Quality

4.8

out of 10

Value Trap

LOW

Price

$16.83

Last close

Models

9/13

Active

Model-by-Model Comparison

Model	Type	LSTA Fair Value	LSTA Upside	LYEL Fair Value	LYEL Upside
Bayesian DCF	Intrinsic	$1.67	-49.3%	$4.48	-73.4%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$3.19	-3.3%	$14.95	-11.2%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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LSTA vs LYEL — Which Stock Is More Undervalued?

LSTA scores higher with a 5.2/10 quality rating vs LYEL's 4.8/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Lisata Therapeutics, Inc. (LSTA) and Lyell Immunopharma, Inc. (LYEL) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

LSTA currently trades at $3.30 with a QOC of 5.2/10, while LYEL trades at $16.83 with a QOC of 4.8/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).