IONS vs IPSC

Ionis Pharmaceuticals, Inc. vs Century Therapeutics, Inc. — Valuation Comparison 2026

By CirclFi Research Team · Updated 2026-06-03 · Data from SEC EDGAR, FRED & GDELT

Quick Summary — IPSC scores higher on quality with 5.9/10 vs IONS's 3.5/10. IONS trades at $72.97 while IPSC trades at $2.17. Both analyzed daily using SEC EDGAR data across 13 institutional models.

IONS

Biotechnology
Ionis Pharmaceuticals, Inc.
Quality
3.5
out of 10
Value Trap
12
SAFE
Price
$72.97
Last close
Models
12/13
Active
VS

IPSC

Biotechnology
Century Therapeutics, Inc.
Quality
5.9
out of 10
Value Trap
24
SAFE
Price
$2.17
Last close
Models
12/13
Active
IONS
2 models active
Quality 3.5/10 — below average
IPSC
2 models active
Limited to 2/13 visible models

IONS vs IPSC — Fair Value Comparison

IONS
$0$29$57$86 Price$72.97 Bayesian …$24.37 (-66.6%) Earnings …$36.24 (-50.5%)
IPSC
$0$1$2$3 Price$2.17 Bayesian …$0.62 (-71.6%) Earnings …$1.16 (-49.5%)
Market Price Model 1 Model 2

Model-by-Model Comparison

ModelType IONS Fair ValueIONS Upside IPSC Fair ValueIPSC Upside
Bayesian DCF Intrinsic $24.37 -66.6% $0.62 -71.6%
Earnings Power Value Intrinsic $36.24 -50.5% $1.16 -49.5%
EROIC Spread Intrinsic $•••.•• ••.•% $•••.•• ••.•%
First Chicago Scenario $•••.•• ••.•% $•••.•• ••.•%
Markov DDM Intrinsic $•••.•• ••.•% $•••.•• ••.•%
ML-RIV Intrinsic $•••.•• ••.•% $•••.•• ••.•%
Dynamic NAV Asset-Based $•••.•• ••.•% $•••.•• ••.•%
PWERM Option-Based $•••.•• ••.•% $•••.•• ••.•%
Regime Cross-Sectional Relative $•••.•• ••.•% $•••.•• ••.•%
Sentiment SOTP Hybrid $•••.•• ••.•% $•••.•• ••.•%
CUCE Ensemble Ensemble $•••.•• ••.•% $•••.•• ••.•%
FTNN Topology Relative $•••.•• ••.•% $•••.•• ••.•%
RCMH-DCF Intrinsic $•••.•• ••.•% $•••.•• ••.•%

IONS vs IPSC — Which Stock Is More Undervalued in 2026?

IPSC scores higher with a 5.9/10 quality rating vs IONS's 3.5/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

How Do IONS and IPSC Valuations Compare?

At $72.97, IONS trades +66.6% above its Bayesian DCF fair value of $24.37, while IPSC at $2.17 trades +71.6% above its estimate of $0.62. IPSC shows a wider gap between price and intrinsic value.

Quality of Company: IONS vs IPSC

IONS earns a Quality of Company score of 3.5/10 compared to IPSC's 5.9/10. This moderate difference suggests one company has an edge in fundamental quality, though both may offer investment merit depending on valuation. The QOC score synthesizes 32 signals spanning profitability margins, revenue growth, free cash flow, capital allocation, and leverage.

Value Trap Risk: IONS vs IPSC

IONS carries a SAFE value trap risk (12/100) while IPSC shows SAFE risk (24/100). Both companies show manageable value trap risk, suggesting their current valuations are not artificially depressed by fundamental deterioration.

Both in Biotechnology

Both IONS and IPSC operate in Biotechnology, which has 566 stocks tracked by CirclFi. Same-industry comparisons provide the most direct insight into relative valuation since both companies face similar regulatory environments, market dynamics, and competitive pressures. Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN), and ensemble methods (CUCE).

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