Is INSM or IOVA more undervalued in 2026?

CirclFi compares Insmed Incorporated (INSM) and Iovance Biotherapeutics, Inc. (IOVA) using 13 institutional-grade valuation models. INSM has a Quality of Company score of 4.0/10 while IOVA scores 5.1/10.

Which is a better buy — INSM or IOVA?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do INSM and IOVA valuations compare?

INSM at $108.37 and IOVA at $4.30 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

INSM vs IOVA Valuation Comparison 2026 — Intrinsic Value Analysis

INSM

Biotechnology

Insmed Incorporated

Quality

4.0

out of 10

Value Trap

SAFE

Price

$108.37

Last close

Models

11/13

Active

IOVA

Biotechnology

Iovance Biotherapeutics, Inc.

Quality

5.1

out of 10

Value Trap

SAFE

Price

$4.30

Last close

Models

11/13

Active

Model-by-Model Comparison

Model	Type	INSM Fair Value	INSM Upside	IOVA Fair Value	IOVA Upside
Bayesian DCF	Intrinsic	$36.85	-66.0%	$1.33	-69.0%
Earnings Power Value	Intrinsic	$64.56	-52.2%	$0.72	-78.7%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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INSM vs IOVA — Which Stock Is More Undervalued?

IOVA scores higher with a 5.1/10 quality rating vs INSM's 4.0/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Insmed Incorporated (INSM) and Iovance Biotherapeutics, Inc. (IOVA) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

INSM currently trades at $108.37 with a QOC of 4.0/10, while IOVA trades at $4.30 with a QOC of 5.1/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).