Is CRL or CSTL more undervalued in 2026?

CirclFi compares Charles River Laboratories Inte (CRL) and Castle Biosciences, Inc. (CSTL) using 13 institutional-grade valuation models. CRL has a Quality of Company score of 7.8/10 while CSTL scores 7.6/10.

Which is a better buy — CRL or CSTL?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do CRL and CSTL valuations compare?

CRL at $181.34 and CSTL at $22.11 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

CRL vs CSTL Valuation Comparison 2026 — Intrinsic Value Analysis

CRL

Diagnostics & Research

Charles River Laboratories Inte

Quality

7.8

out of 10

Value Trap

SAFE

Price

$181.34

Last close

Models

12/13

Active

CSTL

Diagnostics & Research

Castle Biosciences, Inc.

Quality

7.6

out of 10

Value Trap

SAFE

Price

$22.11

Last close

Models

12/13

Active

Model-by-Model Comparison

Model	Type	CRL Fair Value	CRL Upside	CSTL Fair Value	CSTL Upside
Bayesian DCF	Intrinsic	$116.83	-35.6%	$9.55	-56.8%
Earnings Power Value	Intrinsic	$154.38	-14.9%	$1.60	-93.5%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
Markov DDM	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%
RCMH-DCF	Intrinsic	$•••.••	••.•%	$•••.••	••.•%

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CRL vs CSTL — Which Stock Is More Undervalued?

CRL scores higher with a 7.8/10 quality rating vs CSTL's 7.6/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Charles River Laboratories Inte (CRL) and Castle Biosciences, Inc. (CSTL) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

CRL currently trades at $181.34 with a QOC of 7.8/10, while CSTL trades at $22.11 with a QOC of 7.6/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).