Is APRE or AQST more undervalued in 2026?

CirclFi compares Aprea Therapeutics, Inc. (APRE) and Aquestive Therapeutics, Inc. (AQST) using 13 institutional-grade valuation models. APRE has a Quality of Company score of 4.5/10 while AQST scores 5.7/10.

Which is a better buy — APRE or AQST?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do APRE and AQST valuations compare?

APRE at $0.89 and AQST at $4.02 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

APRE vs AQST Valuation Comparison 2026 — Intrinsic Value Analysis

APRE

Pharmaceutical Preparations

Aprea Therapeutics, Inc.

Quality

4.5

out of 10

Value Trap

SAFE

Price

$0.89

Last close

Models

8/13

Active

AQST

Pharmaceutical Preparations

Aquestive Therapeutics, Inc.

Quality

5.7

out of 10

Value Trap

LOW

Price

$4.02

Last close

Models

10/13

Active

Model-by-Model Comparison

Model	Type	APRE Fair Value	APRE Upside	AQST Fair Value	AQST Upside
Bayesian DCF	Intrinsic	$2.30	+157.5%	$1.38	-65.6%
Earnings Power Value	Intrinsic	—	—	$1.22	-70.9%
EROIC Spread	Intrinsic	$•••.••	••.•%	$•••.••	••.•%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$0.80	-10.4%	$0.49	-88.5%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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APRE vs AQST — Which Stock Is More Undervalued?

AQST scores higher with a 5.7/10 quality rating vs APRE's 4.5/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Aprea Therapeutics, Inc. (APRE) and Aquestive Therapeutics, Inc. (AQST) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

APRE currently trades at $0.89 with a QOC of 4.5/10, while AQST trades at $4.02 with a QOC of 5.7/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).