Is ANRO or APRE more undervalued in 2026?

CirclFi compares Alto Neuroscience, Inc. (ANRO) and Aprea Therapeutics, Inc. (APRE) using 13 institutional-grade valuation models. ANRO has a Quality of Company score of 4.7/10 while APRE scores 4.5/10.

Which is a better buy — ANRO or APRE?

Compare intrinsic values from 13 independent models against current market prices. CirclFi also calculates Value Trap scores. This is not financial advice — conduct your own analysis.

How do ANRO and APRE valuations compare?

ANRO at $20.07 and APRE at $0.89 are compared across Bayesian DCF, EPV, EROIC Spread, First Chicago, Markov DDM, and 8 additional models.

ANRO vs APRE Valuation Comparison 2026 — Intrinsic Value Analysis

ANRO

Pharmaceutical Preparations

Alto Neuroscience, Inc.

Quality

4.7

out of 10

Value Trap

SAFE

Price

$20.07

Last close

Models

7/13

Active

APRE

Pharmaceutical Preparations

Aprea Therapeutics, Inc.

Quality

4.5

out of 10

Value Trap

SAFE

Price

$0.89

Last close

Models

8/13

Active

Model-by-Model Comparison

Model	Type	ANRO Fair Value	ANRO Upside	APRE Fair Value	APRE Upside
Bayesian DCF	Intrinsic	$7.28	-63.7%	$2.30	+157.5%
First Chicago	Scenario	$•••.••	••.•%	$•••.••	••.•%
ML-RIV	Intrinsic	$1.91	-90.5%	$0.80	-10.4%
Dynamic NAV	Asset-Based	$•••.••	••.•%	$•••.••	••.•%
PWERM	Option-Based	$•••.••	••.•%	$•••.••	••.•%
Regime Cross-Sectional	Relative	$•••.••	••.•%	$•••.••	••.•%
Sentiment SOTP	Hybrid	$•••.••	••.•%	$•••.••	••.•%
CUCE Ensemble	Ensemble	$•••.••	••.•%	$•••.••	••.•%
FTNN Topology	Relative	$•••.••	••.•%	$•••.••	••.•%

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ANRO vs APRE — Which Stock Is More Undervalued?

ANRO scores higher with a 4.7/10 quality rating vs APRE's 4.5/10. Both stocks are analyzed daily using SEC EDGAR filings across 13 independent models.

Comparing Alto Neuroscience, Inc. (ANRO) and Aprea Therapeutics, Inc. (APRE) across 13 institutional-grade valuation models reveals how each company's intrinsic value stacks up against its market price. CirclFi's engine processes SEC EDGAR 10-K and 10-Q filings, FRED macroeconomic data, and GDELT news sentiment to generate independent fair value estimates daily.

ANRO currently trades at $20.07 with a QOC of 4.7/10, while APRE trades at $0.89 with a QOC of 4.5/10.

Both companies are analyzed with models spanning intrinsic (Bayesian DCF, EPV), scenario-based (First Chicago), regime-switching (Markov DDM, RCMH-DCF), machine learning (ML-RIV, FTNN Topology), and ensemble methods (CUCE).